17th World Congress of the
INTERNATIONAL
PANCREAS & ISLET
TRANSPLANT ASSOCIATION

Lyon, Catholic University, 2-5 July 2019

 

 

 

Preliminary Scientific programTélécharger le programme at a glance

 

Programme at a glance

 

Tuesday July 2, 2019
 
9.00 a.m. - 4.00 p.m.
Pre-congress symposium
The Igls criteria for defining pancreas and islet graft function: time for assessment
Organizing panel: Thierry Berney, Eelco de Koning, Lorenzo Piemonti, Michael Rickels, Peter Stock, Olivier Thaunat


9.00 - 10.00 a.m. - Session 1
Utility and utilization of the Igls criteria
Chairs: Thierry Berney, Michael Rickels

  • The Igls criteria: refresher
    Michael Rickels
  • Real-life application of the criteria: Issues and comparative results (pancreas vs islets)
    Reports from pancreas and islet transplant centers

                              10.00 - 10.30 - Break

10.30 - 12.00 a.m. - Session 2
Assessment and improvement of the Igls criteria
Chairs: Eelco de Koning, James Shaw

  • Pre-transplant metabolic assessment of the patient
    Roger Lehmann
  • Should success criteria depend on the indication for beta cell replacement ?
    Patrik Choudhary
  • How can the Igls criteria be used to impact on patient management?
    James Shaw
  • Should CGM parameters be included in a function score?
    Marie-Christine Vantyghem
  • Interactive debate: needs for improvement

  
                           12.00 - 13.00 - Lunch break


1.00 - 2.00 p.m. - Session 3
Immuno monitoring of beta cell replacement
Chairs: Peter Stock, Olivier Thaunat

  • Current immune monitoring practices
    Peter Stock
  • Significance of DSA monitoring of pancreas or islet grafts
    Olivier Thaunat
  • Pancreas graft biopsy
    Pablo Uva
  • Monitoring for autoimmunity
    George Burke


2.00 - 4.00 p.m. - Session 4
Expanding the application of the Igls criteria
Chairs: Lorenzo Piemonti, Tom Kay

  • Applicability to islet autotransplants
    Melina Bellin
  • Assessing PTDM after beta-cell replacement
    Eelco de Koning
  • Comparing transplants with artificial pancreas: what metrics?
    Tom Kay
  • Definition of success as a function of risk
    Lorenzo Piemonti
  • Questions and discussion

YIC Pre-congress Workshhop
Rockefeller campus

Stream 1 - Clinical cases in Pancreas Procurement

Stream 2 - Islet perfusion and complications simulation

Stream 3 - Discussions in cutting edge advances in Islet and Pancreas Transplantation

 
5.00 - 6.30 p.m.

Opening Ceremony

Lectures Pierre Corvol, President of the Science Academy
  David Kerr, Sansum Diabetes Research Institute, Santa Barbara, CA, USA
 
6.30 - 8.00 p.m.
Welcome cocktail
 
Wednesday July 3, 2019
 
7.30 - 8.30 a.m.
Morning run
 
8.30-10.00 a.m.

Plenary session 1 – Talk show

Opening the echo chamber - Perspectives on curing diabetes

  • What do patients with diabetes really want?
  • Can (could) this be met by islet, pancreas, stem cell replacement?
  • What are patients with diabetes building for themselves?
  • How should we compare the different options ?
  • Can cinical trial results be generalized to all patients with type 1 diabetes ?
  • Who should be recruited to clinical trials ?
Panellists Karen Denoyer, New York, USA
  Jonathan Fridell, Indianapolis,USA
  Frantisek Saudek, Prague, Czech republic
  Tadej Batellino, Ljubljana, Slovenia
 
10.00 - 10.30 a.m.
Richard Lillehei lecture
 
10.30 - 11.00 a.m.
Coffee break
 
11.00 - 11.45 a.m.

Symposium on islet xenotransplantation
Supported by Diatranz Otsuka Ltd
Chair : Shinichi Matsumoto, Japan 

  • Clinical update of islet transplantation at the University of Chicago
    Piotr Witkowski, University of Chicago, USA
  • Challenges of regulatory issues in islet transplantation
    Barbara Barbaro, University of Illinois, Chicago, USA
 
11.00 a.m. - 12.30 p.m.
Oral Communications
 
12.30 - 1.30 p.m.
Lunch Break
 
1.30 - 2.00 p.m.
PITCH
 
2.00 - 3.30 p.m.

State of the Art 1

Organ preservation « Out of the box »

  • Sorting criteria for the marginal pancreas: waste or recondition ?
    Raja Kandaswamy, Minneapolis, USA
  • Normothermic regional perfusion of pancreas and islet donors
    Andrew Sutherland, Edinburgh, UK
  • Hypothermic oxygenated machine perfusion in pancreas/islet transplantation
    VassiliosPapalois, London, UK
  • Oxygen persufflation : a feasible and efficient technique for pancreas reconditioning ?
    Klearchos Papas, Tucson, USA

State of the Art 2

Biotechnology shapes the future for beta cell replacement therapy

  • “House of islets”
    Lorenzo Piemonti, Italy
  • Bioengineering approach to immunosuppression-free islet transplantation
    Haval Shirwan, Louisville, USA
  • Generation of insulin-producing cells from human pancreatic organoids
    Eelco de Koning, Leiden, The Netherlands
 
3.30 - 5.00 p.m.
Oral Communications
 
5.00 - 6.00 p.m.
IPITASciPub.
 
Thursday July 4, 2019
 
7.30 - 8.30 a.m.
Morning run
 
8.30 - 10.00 a.m.

Plenary session 2

Hypes and hopes of the artificial pancreas

  • Current automated insulin delivery systems : what do they really achieve ?
    Alanna Weisman, Toronto, Canada
  • Patient-driven R&D : why-how-what ?
    Kate Farnsworth, Bolton, Canada
  • What will it take to address uncontrolled diabetes with closed-loop technology ?
    Eric Renard, Montpellier, France
  • Risk-benefit assessment of beta-cell replacement vs automated insulin delivery systems
    Patrik Choudhary, London, UK
 
10.00 - 10.30 a.m.
Presidential address/Derek Gray Awards
 
10.30 - 11.00 a.m.
Coffee break
 
11.00 a.m. - 12.30 p.m.
Oral Communications
 
12.30 - 1.30 p.m.
Lunch Break
 
1.30 - 2.00 p.m.
IPITA Business meeting
 
2.00 - 3.30 p.m.

State of the Art 3

Letter to the (gene) editor

  • Genome editing made easy (« Genome editing for dummies » ?)
    Danwei Huangfu, New-York, USA
  • Will gene editing carry pig islets to the clinic ?
    Eckhard Wolf, Munich, Germany
  • Can genome editing produce "universal human cells" for transplantation ?
    Gregory Block, Seattle, USA

State of the Art 4

Type 2 diabetes: a surgical disease ?

  • Phenotypic variability in type 2 diabetes
    Stefano Del Prato, Pisa, Italy
  • Bariatric surgery : reviving the failing beta cells in type 2 diabetes
    speaker to be confirmed
  • Pancreas transplantation : replacing the failing beta cells in type 2 diabetes
    Dixon Kaufmann, Madison, USA
 
3.30 - 5.00 p.m.
Oral Communications
 
5.00 - 6.00 p.m.
IPITASciPub.
 
7.00 - 11.00 p.m.
YIC networking event
 
Friday July 5, 2019
 
7.30-8.30 a.m.
Morning run
 
8.30-10.00 a.m.

State of the Art 5

Immunosuppression tailored for beta-cell replacement

  • Immunometabolism and beta cell replacement
    Marc Donath, Basel, Switzerland
  • Strategies for beta cell replacement: Pancreas vs Islet
    Peter Stock, San Francisco, USA
  • Precision medicine in immunosuppression: how hard can it be ? 
    speaker to be confirmed
  • Tolerance induction in beta cell replacement
    Qizhi Tang, San Francisco, USA

State of the Art 6

Keeping an eye on beta cells : biomarkers to monitor pancreas and islet grafts

  • Imaging beta cells in vivo
    Olof Eriksson, Uppsala, Sweden
  • Alternate transplantation sites to monitor islet histology
    Toby Coates, Adelaide, Australia
  • Immune monitoring of signs of rejection and diabetes recurrence
    Paolo Monti, Milan, Italy
  • Genomics of beta cell death
    Bashoo Naziruddin, Dallas, USA
 
10.00 - 10.30 a.m.
Paul Lacy Lecture
 
10.30 - 11.00 a.m.
Coffee break
 
11.00 - 12.00 a.m.
Oral Communications
 
12.00 - 1.00 p.m.
Dinausor Challenge
 
1.00 - 2.00 p.m.
Lunch Break
 
2.00 - 3.00 p.m.
PITCH presentation finals
 
3.00 - 5.00 p.m.

Plenary session 3

Beta cell grafts for all

  • Organ manufacturing by interspecies blastocyst complementation
    Juan Carlos Izpisua Belmonte, San Diego, USA
  • Islet 3-D bioprinting
    Aart van Appeldorn, Maastricht, The Netherlands
  • Challenges and opportunities of hESC-derived β cells for T1D therapy
    Cristina Nostro, Toronto, Canada
  • Re-create beta cell development in a dish – a source for future cell therapy
    Henrik Semb, Copenhagen, Denmark
 
5.00 - 5.30 p.m.
Conclusions
 
7.00 p.m.
Congress dinner
 

 

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